SCIENTIFIC RESEARCHES ABOUT HEART HEALTH CARE DIETARY SUPPLEMENT There are many worldwide researches defining the high power of the organic components for human heart care supplements manufacturing industry. Scientific pubblications from University in Japan, USA, Italy, Australia,... confirms the quality and efficience of the Organic Lycopene to avoid main human diseases as Parkinson, Alzheimer disease, cancer and others. The scientific staff of Pierre Italy has used all of them as scientific reference to improve, to define our organic dietary supplements... APPLY FOR DISTRIBUTION

SCIENTIFIC RESEARCH TO CREATE LYCOMPLETE® - ITALIAN HEART CARE SUPPLEMENT MANUFACTURING

ENZYME-AIDED EXTRACTION OF LYCOPENE FROM HIGH PIGMENT TOMATO CULTIVARS BY SUPERCRITICAL CARBON DIOXIDE, 2014

Lenucci, De Caroli, Marrese, Andrea Iurlaro, Leonardo Rescio, Volker Böhm, Dalessandro, Gabriella Piro by Dipartimento di Scienze e Tecnologie Biologiche ed Ambientali (Di.S.Te.B.A.), Università del Salento, Italy, PIERRE s.r.l., 73013 Galatina (LE), Italy, Institute of Nutrition, Friedrich Schiller University Jena, Dornburger Straße 25-29, 07743 Jena, Germany
THIS WORK REPORTS A NOVEL ENZYME-ASSISTED PROCESS for lycopene concentration into a freeze-dried tomato matrix and describes the results of laboratory scale lycopene supercritical CO2 (SC-CO2) extractions carried out with untreated (control) and enzyme-digested matrices. The combined use of food-grade commercial plant cell-wall glycosidases (Celluclast/Novozyme plus Viscozyme) allows to increase lycopene (153%) and lipid (137%) concentration in the matrix and rises substrate load onto the extraction vessel (46%) compared to the control. The addition of an oleaginous co-matrix (hazelnut seeds) to the tomato matrix (1:1 by weight) increases CO2 diffusion through the highly dense enzyme-treated matrix bed and provides lipids that are co-extracted increasing lycopene yield. Under the same operative conditions (50 MPa, 86 C, 4 mL min1 SC-CO2 flow) extraction yield from control and Celluclast/Novozyme + Viscozyme- treated tomato matrix/co-matrix mixtures was similar, exceeding 75% after 4.5 h of extraction. However, the total extracted lycopene was 3 times higher in enzyme-treated matrix than control. 2014 Published by Elsevier Ltd.

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Lu Wang, J. Michael Gaziano, Edward P. Norkus, Julie E Buring, and Howard D. Sesso- Associations of plasma carotenoids with risk factors and biomarkers related to cardiovascular disease in middle-aged and older women - Am J Clin Nutr. 2008 September ; 88(3): 747–754. [File 138 AJCN 2008.pdf]

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Peter W. de Leeuw & Aalt Bast - Tomato Extract for Hypertension? Editorial to “The Effects of Natural Antioxidants from Tomato Extract in Treated but Uncontrolled Hypertensive Patients” by E. Paran et al. - Cardiovasc Drugs Ther (2009) 23:107–108 [File 139 CDT 2009.pdf]

Hussein O, Frydman G, Frim H, Aviram M. Lipid Research Laboratory, Government Rebecca Sieff Hospital, P.O. Box 1008, 13100, Safed, Israel - Reduced susceptibility of low density lipoprotein to lipid peroxidation after cholestyramine treatment in heterozygous familial hypercholesterolemic children. Pathophysiology 2001 Aug;8(1):21-28

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CARDIOVASCULAR RISK - PROTECTING YOUR HEALTH
Cardiovascular and coronary heart diseases are the main causes of early death in many developed countries across the world. They are caused by the formation and the development of an atherosclerotic plaque on the internal walls of the arteries. This process is due to the oxidisation of low density lipoproteins (LDL), which produces lipidic deposits (atheromata). LDL is the main carrier of cholesterol into the blood stream. Oxidized LDL (LDLox) are not able to play correctly their role and are removed and destroyed by macrophages. When a LDLox excess occurs, the macrophages become larger, change their aspect and accumulate on the walls of the arteries. The gradual build up of these deposits causes the arteries to narrow and harden, restricting the flow of oxygenated blood to the heart muscle. This can cause angina and, if a coronary artery becomes completely blocked, it can cause permanent damage to the heart muscle or heart attack.

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LYCOMPLETE - LYCOPENE EXTRACTED FROM ORGANIC TOMATOES BY SUPERCRITICAL CO2 FREE OF CHEMICAL SOLVENTS

ORGANIC LYCOPENE TO THE FOOD SUPPLEMENTS INDUSTRY BY PIERRE GROUP - THE PERFECT ANTIOXIDANT MADE IN ITALY

LYCOPENE SOURCES Lycopene is a carotenoid, a group of compounds present in many fresh fruits and vegetables. There are more than 750 types of carotenoids in nature; however, only 20 of these have been found in human blood and tissues. The carotenoid most often present in human blood is lycopene ,followed by b -carotene, lutein and zeaxanthin.

 RED RIPE TOMATOES THE MAIN SOURCE OF LYCOPENE and their derivatives are the main natural source of lycopene giving approximately 85% of all lycopene in the human body. The amount of lycopene in tomatoes depends the quality of fruit, the environment and cultivation procedures. Usually, the content of lycopene in red-ripe tomatoes is 30-80 mg/kg of fresh product, but it could be more than 150-300 mg/kg in some selected species obtained by traditional hybridization techniques.
PROPERTIES OF ORGANIC LYCOPENE the organic lycopene has a very strong antioxidant power, as antioxidant contrasts the destructive action of free radicals in the human body (which are seriously dangerous for the cells and tissues) protects and prevents against several diseases... SEE FULL INFORMATION

Health Prostate Dietary

Lycodeep skin care supplement

Lycomplete heart supplement

Lycosport athlete supplements

Lycocor for Italian market

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Naturmio women for Italian market

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We offer our full dietary, food and health care supplements manufacturing knowledge plus our engineering capabilities to create, design, produce new supplement products, in Private label, for manufacturers and distributors.

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WE PRODUCE ORGANIC LYCOPENE THE MOST IMPORTANT ANTIOXIDANT EXTRACTED FROM RED-RIPE TOMATOS

Pierre Group srl is an Italian manufacturer of organic dietary supplements using made in Italy organic lycopene health care supplements, dietary care supplements manufacturer, organic healthy suppliers, organic medicine pills manufacturing, Italian pharmaceutical technology supply, anticancer medicine vendors, organic lycopene manufacturers. Our mission is to produce the best health and dietary care products for distributors in Europe, USA, Asia Middle East... including the following markets: Italy, Austria, France, USA, Netherlands, England, Scotland, Russia, Spain, Ukraine, Greece, California, Texas, New York, Florida, Illinois, Atlanta in the US, Panama, Australia, Japan, China, India, Chile, Argentina, Brazil, Uruguay, Colombia, Ecuador, Perù, Brasil, Belgium, Saudi Arabia, Oman, Dubai, China, Thailand, Taipei, Finland, Poland, Germany, Norway, England, Romania, Kuwait, Dubai, Oman, UAE, Qatar, Mexico, Uruguay, Paraguay, Costa Rica, Republica Dominicana, Ireland Great Britain, Russia, Scotland, Bolivia, England, Sweden, Canada, the United States, South Korea, Kuwait, China, Japan, Oman, Bahrain, Denmark, Holland, Spain, Colombia, Nicaragua, Puerto Rico, Czech Republic, India, Thailand... supporting the vip wholesale dietary and health supplements distributors worldwide

FOR INFO AND CUSTOMER SERVICES CALL OUR MANUFACTURING FACILITIES: +39.333.6371.644

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PIERRE GROUP SRL "THE ITALIAN ORGANIC DIETARY AND HEALTH LYCOPENE SUPPLEMENTS MANUFACTURING INDUSTRY"

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Export offices in Italy (English + Spanish + Italian): +39.333.6371.644
Sales offices in England UK: +44.7935.999.251

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